Learning Library
The PacificDx learning library is a resource depot for PacificDx materials and related articles in science, genomics, and laboratory medicine.
Articles & Publications
Gunn S et al. Celiac genetic health risk screening by NGS in the family of a child with clinical findings of dermatitis herpetiformis and gluten sensitivity. CAP Today , 2021.
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Gunn S et al. Reference size matching, whole-genome amplification, and fluorescent labeling as a method for chromosomal microarray analysis. (abstract) Journal of Molecular Diagnostics, 2018.
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Gunn S. Commentary—Redefining HER2-Equivocal Breast Cancers: Lessons Learned from Genomic Pathology. The American Journal of Hematology/Oncology®, 2017.
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Phin S et al. Fluorescence in situ Hybridization (FISH)-based Companion Diagnostics in Oncology. Trends in Cancer Research, 2014.
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Moore M et al. Challenges in the Co-development of Companion Diagnostics. Future Medicine, 2014.
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Phin S et al. Genomic Rearrangements for PTEN in Prostate Cancer. Frontiers in Oncology, 2013.
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Moore M et al. Companion Diagnostics and Personalized Medicine: A Review of Molecular Diagnostic Applications. Current Topics in Genetics, 2012.
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Cotter P et al. A New Paradigm for Personalized Medicine and Companion Diagnostics: The Contract Diagnostic Organization. Bentham Open, 2012.
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Literature
Scientific Presentations
Early evaluation site experience with a liquid biopsy kit designed for next generation sequencing of ctDNA.
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Inter-site comparison of performance of an ultra-sensitive sequencing technology for circulating tumor DNA.
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Novel four color probe for simultaneous detection of RET break-apart and PDGFR amplification.
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Useful Articles & Links
Liquid biopsies reveal genetic alterations linked to cancer drug resistance. Broad Institute of MIT and Harvard, September, 2019
‘Liquid biopsy’ promises early detection for cancer. Kaiser J. Science Magazine, 2018
ctDNA and CTCs in Liquid Biopsy — Current Status and Where We Need to Progress. Mini Review. Neumann M et al. Computational and Structural Biotechnology Journal, 2018
Liquid biopsy: monitoring cancer-genetics in the blood. Crowley E et al. Nature Reviews Clinical Oncology, 2013
Must CLIA Labs Give Patients Test Results? Texas Medical Association
Next-Generation Sequencing in the Clinical Laboratory. A Guide to Applied Molecular Testing. Duncan D et al. 2017
College of American Pathologists (CAP)
American Society of Clinical Oncology (ASCO)
American Association of Clinical Chemistry (AACC)