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HER2 testing by Micro-array, resolving tough diagnostic questions

Accurate reporting of HER2 (ERBB2) gene copy number status in newly diagnosed breast and gastric cancers is critical for selecting patients predicted to respond to anti-HER2 therapy. In current clinical practice, tumors are evaluated for HER2 positivity by protein-based immunohistochemistry (IHC) and/or chromosome 17-based fluorescence in situ hybridization (FISH). In the majority of cases, these…
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